Accession 182
Title LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins
Summary Using isogenic LKB1 knockdown cell line pairs and a phospho-specific antibody microarray, we observed that there was a requirement for LKB1 in the phosphorylation of other Akt downstream targets, including Ask1 (Ser(83)), Bad (Ser(136)), FoxO1 (Ser(319)), FoxO4 (Ser(197)), and glycogen synthase kinase 3beta (GSK3beta; Ser(9)).
Journal Cancer Res.
Publish date September, 2008
Corresponding Author Wei Zhou
Array Type Antibody array
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:18794113