Accession |
196 |
Title |
Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance |
Summary |
Reverse-phase protein array revealed that the Ras-dependent downstream targets c-Myc and cyclin B were elevated in cell lines resistant to PX-866 in vivo. |
Journal |
Cancer Res. |
Publish date |
January, 2009 |
Corresponding Author |
Garth Powis |
E-mail |
gpowis@mdanderson.org |
Array Type |
Reverse phase protein array |
Species |
Homo sapiens |
Raw data link |
No relevant experiment link!
|
Link to PubMed |
PubMed ID:19117997
|