Accession 196
Title Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance
Summary Reverse-phase protein array revealed that the Ras-dependent downstream targets c-Myc and cyclin B were elevated in cell lines resistant to PX-866 in vivo.
Journal Cancer Res.
Publish date January, 2009
Corresponding Author Garth Powis
E-mail gpowis@mdanderson.org
Array Type Reverse phase protein array
Species Homo sapiens
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:19117997