| Accession | 228 |
| Title | The platelet integrin alphaIIbbeta3 binds to the RGD and AGD motifs in fibrinogen |
| Summary | A peptide array was used to show that AGD was the minimal binding sequence in HHLGGAKQAGDV and that the receptor recognizes ligands of the form GXGDSC, where X is a hydrophobic or basic residue. This work revises our understanding of the alphaIIbbeta3 specificity and also suggests a new class of antithrombotic agents. |
| Journal | Chem Biol. |
| Publish date | September, 2009 |
| Corresponding Author | Milan Mrksich |
| mmrksich@uchicago.edu | |
| Array Type | Peptide array |
| Species | Homo sapiens |
| Raw data link | No relevant experiment link! |
| Link to PubMed |