Accession | 249 |
Title | Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells |
Summary | Microarray analyses implicated NICD-induced p63 down-regulation in loss of matrix adhesion. In addition, a reverse-phase protein array-based analysis and subsequent loss-of-function studies identified STAT3 as a dominant downstream mediator of the NICD-induced outgrowth. |
Journal | Proc Natl Acad Sci U S A. |
Publish date | March, 2010 |
Corresponding Author | Joan S. Brugge |
joan_brugge@hms.harvard.edu | |
Array Type | Reverse phase protein array |
Species | Homo sapiens |
Raw data link |
Gene Expression Omnibus (www.ncbi.nlm.nih.gov/geo, GSE20285 and GSE20286). |
Link to PubMed |