Accession 260
Title Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium
Summary We now hypothesize that activation of NOD2 in the newborn intestine inhibits TLR4, and that failure of NOD2 signaling leads to NEC through increased TLR4-mediated enterocyte apoptosis. A protein array was performed on NOD2-activated enterocytes to identify novel effector molecules involved.
Journal Gastroenterology
Publish date May, 2010
Corresponding Author David J. Hackam
Array Type Antibody array
Species Homo sapiens; Mus musculus
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:20580721