Accession |
263 |
Title |
Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis |
Summary |
We used reverse-phase protein array to measure the transient changes in the phosphorylation of proteins after IGF-1 stimulation. We developed a computational procedure that integrated mass action modeling with particle swarm optimization to train the model against the experimental data and infer the unknown model parameters. |
Journal |
Cancer Res. |
Publish date |
July, 2010 |
Corresponding Author |
Sergio Iadevaia; Prahlad T. Ram |
E-mail |
siadevai@mdanderson.org; pram@mdanderson.org. |
Array Type |
Reverse phase protein array |
Species |
Homo sapiens |
Raw data link |
No relevant experiment link!
|
Link to PubMed |
PubMed ID:20643779
|