| Accession |
272 |
| Title |
Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis |
| Summary |
In this study, we demonstrate that downregulation of PHD2 leads to increased tumor growth in a hormone-dependent mammary carcinoma mouse model. An angiogenesis-related antibody array identified, amphiregulin to be increased in the absence of PHD2 and normalized after PHD2 reconstitution. |
| Journal |
Oncogene |
| Publish date |
September, 2010 |
| Corresponding Author |
RH Wenger |
| E-mail |
roland.wenger@access.uzh.ch |
| Array Type |
Antibody array |
| Species |
Homo sapiens |
| Raw data link |
No relevant experiment link!
|
| Link to PubMed |
PubMed ID:20856199
|
