Accession |
319 |
Title |
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN) |
Summary |
We performed antibody-array screening in conjunction with biotin-switch assays to look for S-nitrosylated proteins. Using this combination of techniques, we found that phosphatase with sequence homology to tensin (PTEN) is selectively S-nitrosylated by low concentrations of NO at a specific cysteine residue (Cys-83). |
Journal |
Proc Natl Acad Sci U S A. |
Publish date |
June, 2011 |
Corresponding Author |
Takashi Uehara |
E-mail |
uehara@pharm.okayama-u.ac.jp |
Array Type |
Antibody array |
Species |
|
Raw data link |
No relevant experiment link!
|
Link to PubMed |
PubMed ID:21646525
|