Accession 495
Title Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity
Summary Here, we present a functional MTB proteome microarray covering most of the proteome and an ORFome library. We demonstrate the broad applicability of the microarray by investigating global protein-protein interactions, small-molecule-protein binding, and serum biomarker discovery, identifying 59 PknG-interacting proteins, 30 bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) binding proteins, and 14 MTB proteins that together differentiate between tuberculosis (TB) patients with active disease and recovered individuals.
Journal Cell Rep.
Publish date December, 2014
Corresponding Author Tao SC
Array Type Proteome array
Species Homo sapiens; Mycobacterium tuberculosis
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Link to PubMed

PubMed ID:25497094