Accession 497
Title Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients
Summary Using microarrays spotted with >8000 human proteins, we assessed the diversity of Ab responses modulated by treatment with CTLA-4 blockade and GM-CSF. We find that advanced prostate cancer patients who clinically respond to treatment also develop enhanced Ab responses to a higher number of Ags than nonresponders.
Journal J Immunol
Publish date September, 2012
Corresponding Author Lawrence Fong
Array Type Antibody array
Species Homo sapiens
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PubMed ID:22956585