| Accession | 505 |
| Title | Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis |
| Summary | By performing kinase assays with site-specifically phospho- and glyco-modified CK2α in combination with CK2β and Pin1 binding partners on human protein microarrays, we show that the kinase substrate selectivity of CK2 is modulated by these specific post-translational modifications. This study suggests how a promiscuous protein kinase can be regulated at multiple levels to achieve particular biological outputs. |
| Journal | Nat Chem Biol. |
| Publish date | January, 2012 |
| Corresponding Author | Philip A Cole |
| pcole@jhmi.edu | |
| Array Type | Proteome array |
| Species | Homo sapiens |
| Raw data link | |
| Link to PubMed |