Accession | 508 |
Title | IgM Abs to Apoptosis-associated Determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells |
Summary | Herein, we show that the immune response to neoantigenic determinants on apoptotic thymocytes is dominated by Abs to oxidation-associated Ags, phosphorylcholine (PC), a head group that becomes exposed during programmed cell death, and malondialdehyde (MDA), a reactive aldehyde degradation product of polyunsaturated lipids produced following exposure to reactive oxidation species. |
Journal | J Immunol |
Publish date | May, 2009 |
Corresponding Author | Gregg J. Silverman |
gsilverman@ucsd.edu | |
Array Type | Proteome array |
Species | Mus musculus |
Raw data link | |
Link to PubMed |