Accession 516
Title Diagnosis of Alzheimer's disease based on disease-specific autoantibody profiles in human sera
Summary Using human protein microarrays to characterize the differential expression of serum autoantibodies in AD and non-demented control (NDC) groups, we identified potential diagnostic biomarkers for AD. The differential significance of each biomarker was evaluated, resulting in the selection of only 10 autoantibody biomarkers that can effectively differentiate AD sera from NDC sera with a sensitivity of 96.0% and specificity of 92.5%.
Journal PLoS One
Publish date August, 2011
Corresponding Author Robert Nagele
Array Type Proteome array
Species Homo sapiens
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Link to PubMed

PubMed ID:21826230