Accession | 636 |
Title | Designing Two-Dimensional Protein Arrays through Fusion of Multimers and Interface Mutations |
Summary | We have combined fusion of oligomers with cyclic symmetry and alanine substitutions to eliminate clashes and produce proteins that self-assemble into 2-D arrays upon addition of calcium ions. Using TEM, AFM, small-angle X-ray scattering, and fluorescence microscopy, we show that the designed lattices which are 5 nm high with p3 space group symmetry and 7.25 nm periodicity self-assemble into structures that can exceed 100 μm in characteristic length. |
Journal | Nano Lett. |
Publish date | August, 2015 |
Corresponding Author | François Baneyx |
baneyx@uw.edu | |
Array Type | Technological development of protein array |
Species | |
Raw data link | No relevant experiment link! |
Link to PubMed |