Accession 636
Title Designing Two-Dimensional Protein Arrays through Fusion of Multimers and Interface Mutations
Summary We have combined fusion of oligomers with cyclic symmetry and alanine substitutions to eliminate clashes and produce proteins that self-assemble into 2-D arrays upon addition of calcium ions. Using TEM, AFM, small-angle X-ray scattering, and fluorescence microscopy, we show that the designed lattices which are 5 nm high with p3 space group symmetry and 7.25 nm periodicity self-assemble into structures that can exceed 100 μm in characteristic length.
Journal Nano Lett.
Publish date August, 2015
Corresponding Author François Baneyx
Array Type Technological development of protein array
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:25986921