Accession | 646 |
Title | The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity |
Summary | We developed a novel mouse anti-hPDPN mAb, LpMab-7, which is more sensitive than D2-40 and NZ-1, using the Cancer-specific mAb (CasMab) method. The epitope of LpMab-7 was shown to be entirely different from that of NZ-1, a neutralizing mAb against the PLAG domain according to an inhibition assay and lectin microarray analysis. |
Journal | Oncotarget |
Publish date | September, 2015 |
Corresponding Author | Yukinari Kato |
yukinarikato@med.tohoku.ac.jp | |
Array Type | Lectin array |
Species | Homo sapiens |
Raw data link | No relevant experiment link! |
Link to PubMed |