Accession 648
Title Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors
Summary This study explored the activated and interconnected signaling network of KRAS mutant lung adenocarcinomas (AD) to identify novel therapeutic targets.Thirty-four KRAS mutant (MT) and twenty-four KRAS wild-type (WT) frozen biospecimens were obtained from surgically treated lung ADs. Samples were subjected to Laser Capture Microdissection and Reverse Phase Protein Microarray analysis to explore the expression/activation levels of 150 signaling proteins along with co-activation concordance mapping.
Journal Oncotarget
Publish date September, 2015
Corresponding Author Pierobon M
Array Type Reverse phase protein array
Species Homo sapiens
Raw data link No relevant experiment link!
Link to PubMed

PubMed ID:26468985