Accession | 72 |
Title | Tudor, MBT and chromo domains gauge the degree of lysine methylation |
Summary | Here, we describe a protein-array approach for identifying methyl-specific interacting proteins. We found that not only chromo domains but also tudor and MBT domains bind to methylated peptides from the amino-terminal tails of histones H3 and H4. Binding specificity observed on the protein-domain microarray was corroborated using peptide pull-downs, surface plasma resonance and far western blotting. |
Journal | EMBO Rep. |
Publish date | April, 2006 |
Corresponding Author | Mark T Bedford |
mtbedford@mdanderson.org | |
Array Type | Proteome array |
Species | Muti-species |
Raw data link | No relevant experiment link! |
Link to PubMed |