Accession PMDE141
Name Inferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: a Study of OspC Proteins of Borrelia burgdorferi
Description We developed bioinformatics methods to systematically analyze the relationship between local sequence/structure variation and cross-reactive antibody binding patterns among variants of a polymorphic antigen, and this method can be applied to other polymorphic antigens for which immune response data is available for multiple variants.
Publication Experimental infections of the reservoir species Peromyscus leucopus with diverse strains of Borrelia burgdorferi, a Lyme disease agent (Go to PubMed)
Provider Elisabeth Baum
Species Homo sapiens
Subspecies Empty
Array type Proteome array
Sample Serum
Number of array 1
Array(1) OspC Protein Microarray
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Link to GEO