| Accession |
PMDE148 |
| Name |
Profiling antibody function on antigen arrays |
| Description |
Antigen specific C3 deposition can be used as an additional parameter in immune response monitoring. This is exemplified by comparing the coordinates of antigens, used for the diagnosis of systemic lupus erythematosus, of normal and autoimmune serum samples in a two-dimensional space derived from C3 deposition and antibody binding. Since cleavage fragments of C3 mediate important immunological processes we propose that measurement of their deposition on antigen microarrays, in addition to antibody profiling, can provide useful functional signature about the tested serum. |
| Publication |
Detection of complement activation on antigen microarrays generates functional antibody profiles and helps characterization of disease-associated changes of the antibody repertoire
(Go to PubMed)
|
| Provider |
József Prechl |
| Species |
Homo sapiens |
| Subspecies |
Empty
|
| Array type |
Antibody array |
| Sample |
Serum |
| Number of array |
120 |
| Array(1) |
AbC ELTE_human_960_v1
|
| Raw data |
download
|
| Experiment details |
download
|
| Analysis report |
No relevant analysis report. If you want to analyse this data, please contact us. |
| Link to GEO |
GSE12943
|
