Accession PMDE32
Name IgG antibody profiling of Leptospira interrogans serovar Copenhageni in infected and non-infected subjects using protein microarray
Description Leptospirosis is the most widespread zoonotic disease in the world. The lack of an adequate laboratory test is a major barrier for the diagnosis, especially during the early stages of illness, when antibiotic therapy is most effective. Therefore, there is a critical need for an efficient diagnostic test for this life threatening disease. In order to identify new targets that could be used as diagnostic makers for leptopirosis, we constructed a protein microarray chip comprising 61% of Leptospira interrogans proteome and investigated the IgG response against leptospiral antigens from 274 individuals, including 80 acute-, 80 convalescent-phase patients and 114 healthy control subjects from regions with endemic, high endemic and no endemic transmission of leptospirosis.
Publication Identification of seroreactive proteins of Leptospira interrogans serovar copenhageni using a high-density protein microarray approach (Go to PubMed)
Provider Carolina Lessa Aquino
Species Homo sapiens
Subspecies Empty
Array type Proteome array
Sample Serum
Number of array 274
Array(1) UCI Leptospira interrogans serovar Copenhageni Protein Microarray
Raw data download
Experiment details download
Analysis report No relevant analysis report. If you want to analyse this data, please contact us.
Link to GEO