Accession |
PMDE39 |
Name |
Identification of Proteins Binding Coding and Non-coding Human RNAs using Protein Microarrays |
Description |
We describe a refined approach to identify new human RNA-protein interactions. In vitro transcribed labeled RNA is bound to ~9,400 human recombinant proteins spotted on protein microarrays. This approach identified 137 RNA-protein interactions for 10 human coding and non-coding RNAs, including an interaction between Staufen 1 protein and TP53 mRNA that promoted the latter’s stability. RNA hybridization to protein microarrays allows rapid identification of human RNA-protein interactions on a large scale. |
Publication |
Identification of Proteins Binding Coding and Non-coding Human RNAs using Protein Microarrays
(Go to PubMed)
|
Provider |
Kun Qu |
Species |
Homo sapiens |
Subspecies |
Empty
|
Array type |
Proteome array |
Sample |
Nucleic acid |
Number of array |
10 |
Array(1) |
Invitrogen ProtoArray v5.0
|
Raw data |
download
|
Experiment details |
download
|
Analysis report |
No relevant analysis report. If you want to analyse this data, please contact us. |
Link to GEO |
GSE34794
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