Accession PMDE59
Name FIA plasma induces arthritis in naive mice
Description Plasma collected from mice with FIA were pooled, and 0.3 ml was injected intravenously into 6-week-old na?ve SJL mice on days 0 and 2. Synovial antigen array profiling of plasma from the arthritic recipient mice demonstrated autoreactive B-cell responses against peptides representing native fibrinogen and citrullinated fibrinogen, and further epitope spreading resulting in additional targeting of fibronectin, collagen type V, cartilage gp39, and clusterin.
Publication Autoimmunity against Fibrinogen Mediates Inflammatory Arthritis in Mice (Go to PubMed)
Provider William Robinson
Species Canis lupus familiaris
Subspecies Empty
Array type Proteome array
Sample Cell lysate
Number of array 8
Array(1) Synovial protein array 0.5K v2.0
Raw data download
Experiment details download
Analysis report analysis report download
Link to GEO