Accession | PMDE59 |
Name | FIA plasma induces arthritis in naive mice |
Description | Plasma collected from mice with FIA were pooled, and 0.3 ml was injected intravenously into 6-week-old na?ve SJL mice on days 0 and 2. Synovial antigen array profiling of plasma from the arthritic recipient mice demonstrated autoreactive B-cell responses against peptides representing native fibrinogen and citrullinated fibrinogen, and further epitope spreading resulting in additional targeting of fibronectin, collagen type V, cartilage gp39, and clusterin. |
Publication | Autoimmunity against Fibrinogen Mediates Inflammatory Arthritis in Mice (Go to PubMed) |
Provider | William Robinson |
Species | Canis lupus familiaris |
Subspecies | Empty |
Array type | Proteome array |
Sample | Cell lysate |
Number of array | 8 |
Array(1) | Synovial protein array 0.5K v2.0 |
Raw data | download |
Experiment details | download |
Analysis report | analysis report download |
Link to GEO |