| Accession |
492 |
| Title |
Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs |
| Summary |
This study focused on the identification of molecular mechanisms causing resistance against the anti-ERBB2-directed therapeutic antibodies trastuzumab and pertuzumab presently used to treat patients with ERBB2-amplified breast cancer. Drug impact was quantified in cell viability assays and on the proteomic level using reverse-phase protein arrays. |
| Journal |
Oncogenesis |
| Publish date |
July, 2012 |
| Corresponding Author |
U Korf |
| E-mail |
u.korf@dkfz.de |
| Array Type |
Reverse phase protein array |
| Species |
Homo sapiens |
| Raw data link |
PMDE34
|
| Link to PubMed |
PubMed ID:23552733
|
