Accession | 525 |
Title | Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies |
Summary | We identify human kynureninase (KYNU) and splicing factor 3b subunit 3 (SF3B3) as the primary conserved, vertebrate self-antigens recognized by the 2F5 and 4E10 antibodies, respectively. 2F5 binds the H4 domain of KYNU which contains the complete 2F5 linear epitope (ELDKWA). |
Journal | J Exp Med. |
Publish date | January, 2013 |
Corresponding Author | Garnett Kelsoe |
ghkelsoe@duke.edu | |
Array Type | Proteome array |
Species | Homo sapiens |
Raw data link | |
Link to PubMed |