Accession 525
Title Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
Summary We identify human kynureninase (KYNU) and splicing factor 3b subunit 3 (SF3B3) as the primary conserved, vertebrate self-antigens recognized by the 2F5 and 4E10 antibodies, respectively. 2F5 binds the H4 domain of KYNU which contains the complete 2F5 linear epitope (ELDKWA).
Journal J Exp Med.
Publish date January, 2013
Corresponding Author Garnett Kelsoe
E-mail ghkelsoe@duke.edu
Array Type Proteome array
Species Homo sapiens
Raw data link

PMDE142

Link to PubMed

PubMed ID:23359068