Accession | 625 |
Title | Broad Spectrum Antibodies to Self-Antigens and Cytokines in RAG Deficiency |
Summary | By using multiple methods (microarray, ELISA and multiplex bead technology), we have consistently identified a distinctive signature of anti-cytokine antibodies in patients with RAG-dependent immunodeficiencies, especially in those with CID-G/AI and a history of severe viral infections. These autoantibodies were not detected in a large panel of patients with other forms of primary immunodeficiency, and may therefore represent a novel biomarker panel of this condition. |
Journal | J. Clinical Investigation |
Publish date | In press, 2015 |
Corresponding Author | Christopher H. Contag |
ccontag@stanford.edu | |
Array Type | Proteome array |
Species | Homo sapiens |
Raw data link | |
Link to PubMed |